Methyl Cellulose (MC)

Methyl Cellulose (MC) 1.Methoxy:27.5-31.5% 2.Gelation temperature:55.0-55.0 C 3.Viscosity:5-200000cps

Methyl Cellulose (MC)

Specification: 1. Standard: Q/SHD005-2002

Item	55HD
Methoxy group (WT%)	27.0-­32.0
Gel temperature (°C)	50.0-­55.0
Loss on drying (WT%)	≤5.0
Residue on ignition (WT%)	≤1.0
pH (1% aq. solution, 25°C)	4.0-8.0

2. Viscosity

NDJ-1		B type Viscosimeter
Rating Viscosity(mPa.s)	Range	Rating Viscosity(mPa.s)	Range
400	350-500	400	350-500
1500	1300-1800	1500	1300-1800
4000	3600-4800	3500	3000-4500
6000	5400-7000	5000	4000-6000
10000	9000-12000	9000	8000-10000
20000	18000-24000	18000	16000-20000
40000	36000-48000	30000	24000-36000
60000	54000-70000	35000	28000-42000
75000	68000-85000	40000	32000-48000
100000	90000-120000	50000	40000-60000
150000	130000-160000	60000	50000-70000
200000	160000	75000	≥65000

3. Product code nomenclature.

III. Physical properties:a) Out looking:HPMC is a white or light gray pellet or fibril power with odorless.b) Solubility: hardly dissolves in waterless ethanol, aether or -acetone. Separate, expands, in hot water with temperature about 80 to 90. swiftly dissolves when cool down. The solution is very stable. Gelatin at high temperature. Good humectants with good dispersibility, adhesive, thickener, emulsification, water keep ability and film forming ability and oil resistance. The film formed possesses good toughness, flexibility and transparent. It can dissolve in some organic solvents or some water-organic components. Can be mixed with other emulsification agent due to non hydronium structure but easy salt out. Solution is stabilized at PH2-12.c)Density:0.20-0.60g/cm3 with density about 1.3g/cm3.

IV. Dissolving Process.MC will agglomerate when directly added to water and then dissolve. In this way it dissolves very slow and hard. Suggested methods as followers:1. In hot water.MC does not dissolve in hot water. The primary HPMC can be uniformly disperse in hot water. Then cool down in two ways:a) Add hot water in container and heated to over 70. Add MC gradually while slowly, stir. At the beginning, MC float on the top of water, then turns into slurry state stir and cool down.b) Add water in container to 1/3 or 2/3 of its content. Heated to over 70 add MC by sequence of a). Make it disperse to form slurry state. Add cool water or ice to the resideual content, stir and cool down the mixture.2. Powder combination.Mix MC with identical volume of other powder, disperses them sufficiently then add water to the mixture result MC dissolves. without agglomeration.3.Organic solvent wet.Dispersed or wet with orgnic solvents such as ethanol, glycol or oil, then add water can cause MC completely dissolves.

V. Application.Chemical ingredient MC is widely used as thickener, protective glue, auxiliary emulsification agent, coloring matter, adhesive of tablets or coating forming agent. Oral defecation agent as well as bases collutory and eye drop agent. Main raw materials of Oral defecation agent and eye drop agent. Also, it can be used as framework material. MC can be made to hydrophilic sol framework. Micro hole film coating or multi layer coating film it controlled released matrix agent. MC with low viscosity is ususlly used as emulsification agent of water packed oil emulsion while MC with high viscosity can be used as thickener, adhesive agent suspending agent and tablets agglutinate. MC can also be mixed with HPMC as film coating of tablets.

Methyl Cellulose (MC)